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Complete workflows

run_omics_braid()
Run the complete OmicsBraid workflow on sample-level data
run_omics_braid_summary()
Run OmicsBraid from externally estimated summary statistics
braid_results_table()
Create a one-row-per-entity master result table
write_omics_braid()
Export OmicsBraid results

Data input and harmonization

omics_braid_data()
Construct an OmicsBraid data object
as_omics_braid_data()
Coerce supported objects to OmicsBraid data
validate_omics_braid_data()
Validate an OmicsBraid data object
read_omics_braid()
Read OmicsBraid input files
harmonize_entities()
Harmonize assay-specific feature identifiers to common entities
score_pathways()
Score pathways within each omic layer
orient_omics()
Harmonize the sign orientation of omic-layer effects

Effect estimation and covariance

estimate_effects()
Estimate layer-specific standardized effects
bootstrap_effect_covariance()
Estimate cross-omic effect covariance by matched-subject bootstrap
bootstrap_effect_intervals()
Bootstrap confidence intervals for layer-specific standardized effects
bootstrap_consensus_intervals()
Bootstrap confidence intervals for GLS consensus effects

Cross-omic inference

integrate_effects()
Integrate effects across omic layers and quantify heterogeneity
empirical_omics_tests()
Empirically calibrate OmicsBraid omnibus and heterogeneity tests
test_equivalence()
Test practical equivalence to a negligible effect region
test_braid_trend()
Test ordered cross-omic effect trajectories with generalized least squares
classify_braids()
Classify cross-omic braid patterns using inferential evidence
braid_pattern_probabilities()
Quantify uncertainty in effect-braid geometry

Visualization

plot_evidence_forest()
Plot an Omics Evidence Forest
plot_effect_braid()
Plot an Effect Braid
plot_concordance_map()
Plot concordance versus integrated significance
plot_braid_heatmap()
Plot a braid heatmap across entities and omics

Simulation

simulate_braid_data()
Simulate multi-omics data with known braid patterns